| No | Size | Price | Availability | |
| ARP80781-62 | 50ul | 1500.00 | In Stock |  |
| ARP80781-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 80781 |
| Isotype: | IgG | Swiss Prot: | P39060 |
| purity: | Affinity purification |
| Background: |
| This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Three transcripts have been identified for this gene. |
| Reactivity | Human, Mouse |
| Tested applications | IHC IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 178 kDa |
| Recommended Dilutions |
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human Collagen XVIIIalpha 1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Collagen alpha-1(XVIII) chain [Precursor], Endostatin, COIA1 |
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