TF2H2 Rabbit Polyclonal Antibody
| No |
Size |
Price |
Availability |
|
| ARP2966-61 |
50ul |
1500.00 |
In Stock |
 |
| ARP2966-61 |
100ul |
2000.00 |
In Stock |
|
| Source: |
Rabbit |
Gene Id: |
2966 |
| Isotype: |
IgG |
Swiss Prot: |
Q13888 |
| purity: |
Affinity purification |
| Background: |
| This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of this gene within the centromeric copy of the duplication has been described in the literature. It is reported to be different by either two or four base pairs; however, no sequence data is currently available for the centromeric copy of the gene |
| Reactivity |
Human, Mouse, Rat |
| Tested applications |
WB |
| Clonality |
Polyclonal Antibody |
| Calculated MW |
62 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen |
A synthetic peptide derived from human TF2H2 |
| Storage |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym |
Basic transcription factor 2 44 kDa subunitBTF2-p44General transcription factor IIH polypeptide 2 |
This product is for research use only, not for diagnostic or therapeutic use！
