| No | Size | Price | Availability | |
| ARP9902-61 | 50ul | 1500.00 | In Stock |  |
| ARP9902-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 9902 |
| Isotype: | IgG | Swiss Prot: | Q9UBG0 |
| purity: | Affinity purification |
| Background: |
| MRC2 May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 167 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human MRC2 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | C-type lectin domain family 13 member E, C-type mannose receptor 2, CD280, CLEC13E, ENDO180, endocytic receptor (macrophage mannose receptor family), Endocytic receptor 180, FLJ35911, KIAA0709, Macrophage mannose receptor 2, mannose receptor, C type 2, MR |
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