Source: | Rabbit | Gene Id: | 151648 |
Isotype: | IgG | Swiss Prot: | Q5FBB7 |
purity: | Affinity purification |
Background: |
SGO1 Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the STAG2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by ESPL1/separase at anaphase. |
Reactivity | Human |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 64 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide derived from human SGOL1 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | hSgo1, Serologically defined breast cancer antigen NY-BR-85, SGOL1, Shugoshin-like 1 |
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