| No | Size | Price | Availability | |
| ARP9855-61 | 50ul | 1500.00 | In Stock |  |
| ARP9855-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 9855 |
| Isotype: | IgG | Swiss Prot: | O94887 |
| purity: | Affinity purification |
| Background: |
| Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Interacts with PLXNA1. Interaction with PLXNA1 or PIP5K1C lowers its guanine nucleotide exchange activity. Dissociates from PLXNA1 when SEMA3A binds to the receptor.Interacts with PIP5K1C via its FERM domain. The interaction with PIP5K1C is enhanced by SEMA3A binding. 2 isoforms of the human protein are produced by alternative splicing. |
| Reactivity | Human, Mouse |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 119 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A synthetic peptide derived from human FIR |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | FERM, RhoGEF and pleckstrin domain protein 2, FGD1-related Cdc42-GEF, FIR, FRG, PLEKHC3 |
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