Source: | Rabbit | Gene Id: | 80824 |
Isotype: | IgG | Swiss Prot: | Q9BY84 |
purity: | Affinity purification |
Background: |
The activation of mitogen-activated protein kinase (MAPK) cascades transduces various extracellular signals to the nucleus to induce gene expression, cell proliferation, differentiation, cell cycle arrest, and apoptosis. For full activation of MAPKs, dual-specificity kinases phosphorylate both threonine and tyrosine residues in MAPK TXY motifs. MKPs are dual-specificity phosphatases that dephosphorylate the TXY motif, thereby negatively regulating MAPK activity.[supplied by OMIM] |
Reactivity | Human, Mouse |
Tested applications | WB IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 73 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide derived from human DUSP16 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Dual specificity protein phosphatase 16, DUS16, DUSP16, EC 3.1.3.16, EC 3.1.3.48, KIAA1700, MAP kinase phosphatase 7, MAP kinase phosphatase-7, Mitogen-activated protein kinase phosphatase 7, MKP7 |
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