Source: | Rabbit | Gene Id: | 9227 |
Isotype: | IgG | Swiss Prot: | O95237 |
purity: | Affinity purification |
Background: |
LRAT Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments. Belongs to the H-rev107 family. LRAT activity is up-regulated by dietary vitamin A. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 27 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide derived from human LRAT |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | LCA14, Lecithin retinol acyltransferase, lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase), LRAT, MGC33103, Phosphatidylcholine--retinol O-acyltransferase |
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