| No | Size | Price | Availability | |
| ARP10612-61 | 50ul | 1500.00 | In Stock |  |
| ARP10612-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 10612 |
| Isotype: | IgG | Swiss Prot: | O75382 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 81 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human TRIM3 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Tripartite motif-containing protein 3, RING finger protein 22, Brain-expressed RING finger protein, RING finger protein 97, TRIM3, BERP, RNF22, RNF97 |
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