Source: | Rabbit | Gene Id: | 9440 |
Isotype: | IgG | Swiss Prot: | Q9NVC6 |
purity: | Affinity purification |
Background: |
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. |
Reactivity | Human, Mouse |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 73 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide derived from human MED17 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | ARC77, CRSP complex subunit 6, DRIP80, activator-recruited cofactor 77 kDa component, cofactor required for Sp1 transcriptional activation subunit 6, thyroid hormone receptor-associated protein complex 80 kDa component, transcriptional coactivator CRSP77 |
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