Source: | Rabbit | Gene Id: | 540 |
Isotype: | IgG | Swiss Prot: | P35670 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a polypeptide that acts as a membrane copper-transport protein. Defects in this gene are the cause of Wilson disease (WD). WD is an autosomal recessive disorder of copper metabolism in which copper cannot be incorporated into ceruloplasmin in liver, and cannot be excreted from the liver into the bile. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Reactivity | Human, Mouse, Rat |
Tested applications | IHC IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 157 kDa |
Recommended Dilutions |
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide derived from human ATP7B |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | ATP7B, ATPase, Cu(2+)- transporting, beta polypeptide, ATPase, Cu++ transporting, beta polypeptide, Copper pump 2, Copper-transporting ATPase 2, PWD, WC1, WD, Wilson disease-associated protein, WND, WND/140 kDa |
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