| No | Size | Price | Availability | |
| ARP10482-61 | 50ul | 1500.00 | In Stock |  |
| ARP10482-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 10482 |
| Isotype: | IgG | Swiss Prot: | Q9UBU9 |
| purity: | Affinity chromatography |
| Background: |
| NXF1 Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with THOC4 and THOC5. Belongs to the NXF family. Heterodimer with NXT1. Interacts (via NTF2 domain) with NXT1. The formation of NXF1/NXT1 heterodimers is required for the NXF1-mediated nuclear mRNA export. Interacts with NXT2, E1B-AP5, RAE1, THOC4 and with several nucleoporins. Is part of the exon junction complex (EJC) containing NCBP1, NCBP2, RNPS1, RBM8A, SRRM1, NXF1, RENT1, RENT2, RENT3A, RENT3B, THOC4 and/or REFBP2. Found in a mRNA complex with RENT3A and RENT3B. Interacts with FYTTD1/UIF, EIF4A3, NUPL2 and THOC5. Interacts with Saimiriine herpesvirus 2 TIP protein |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 70 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
|
| Immunogen | A synthetic peptide derived from human NXF1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | DKFZp667O0311, MEX67, mRNA export factor TAP, Nuclear RNA export factor 1, NXF1, TAP, tip associating protein, Tip-associated protein, Tip-associating protein |
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