Source: | Rabbit | Gene Id: | 8569 |
Isotype: | IgG | Swiss Prot: | Q9BUB5 |
purity: | Affinity chromatography |
Background: |
Mnk1 a CAM kinase of the MAPKKAPK family that can regulate translation. Following activation by MAP kinases, Mnk1 phosphorylates eIF4E at Ser209, increasing its affinity for the 7-methylguanosine-containing mRNA cap. Two MAPK phosphorylation sites in mouse Mnk1 (Thr197 and Thr202) are essential for its kinase activity. Three alternatively spliced human isoforms have been described. |
Reactivity | Human, Mouse |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 51 kDa |
Recommended Dilutions |
WB 1:500-1:3000
|
Immunogen | A synthetic peptide derived from human MKNK1 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | MAP kinase interacting kinase 1, MAP kinase interacting serine/threonine kinase 1, MAP kinase signal-integrating kinase 1, MAP kinase-interacting serine/threonine kinase 1, MAP kinase-interacting serine/threonine-protein kinase 1, MKNK1, MNK1 |
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