
| Source: | Rabbit | Gene Id: | 5980 |
| Isotype: | IgG | Swiss Prot: | O60673 |
| purity: | Affinity purification |
| Background: |
| REV3 is the DNA polymerase zeta catalytic subunit. Catalyzes the production of N diphosphate + {DNA}N from N deoxynucleoside triphosphate. Involved in translesion synthesis and required for the production of UV- and other DNA fork-blocking-induced mutations, as well as the majority of spontaneous mutations. |
| Reactivity | Human, Mouse |
| Tested applications | IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 352 kDa |
| Recommended Dilutions |
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human REV3L |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | DNA polymerase zeta catalytic subunit, DPOLZ, DPOZ, EC 2.7.7.7, POLZ, REV3L, SEZ4, Seizure-related protein 4, hREV3 |
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