| No | Size | Price | Availability | |
| ARP326-61 | 50ul | 1500.00 | In Stock |  |
| ARP326-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 326 |
| Isotype: | IgG | Swiss Prot: | O43918 |
| purity: | Affinity chromatography |
| Background: |
| AIRE Transcriptional regulator that binds to DNA as a dimer or as a tetramer, but not as a monomer. Binds to G-doublets in an A/T-rich environment; the preferred motif is a tandem repeat of 5'-. ATTGGTTA-3' combined with a 5'-TTATTA-3' box. Binds to nucleosomes. Binds to chromatin and interacts selectively with histone H3 that is not methylated at 'Lys-4', not phosphorylated at 'Thr-3' and not methylated at 'Arg-2'. |
| Reactivity | Human, Mouse |
| Tested applications | WB IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 60 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human AIRE |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | AIRE, AIRE1, APECED, APECED protein, APS1, APSI, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, Autoimmune regulator, PGA1 |
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