Source: | Rabbit | Gene Id: | 8805 |
Isotype: | IgG | Swiss Prot: | O15164 |
purity: | Affinity chromatography |
Background: |
TRIM24 an atypical protein kinase that functions as a transcriptional coactivator. Originally identified as a mammalian protein that enhances the AF-2 activity of the retinoid X receptor (RXR) in a yeast genetic screen. Binds to nuclear receptors in an agonist and AF2-activating domain (AF2-AD) dependent manner. Binding to the agonist-nuclear receptor complex induces its own hyperphosphorylation as well as the phosphorylation of TFIIEa, TAFII28, and TAFII55. |
Reactivity | Human, Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 117 kDa |
Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human TRIM24 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | hTIF1, PTC6, RING finger protein 82, RNF82, TF1A, TIF1, TIF1-alpha, TIF1A, TIF1ALPHA, Transcription intermediary factor 1-alpha, transcriptional intermediary factor 1, TRIM24, tripartite motif protein 24, tripartite motif-containing 24, Tripartite motif-c |
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