Source: | Rabbit | Gene Id: | 10403 |
Isotype: | IgG | Swiss Prot: | O14777 |
purity: | Affinity chromatography |
Background: |
HEC1 plays an essential role in chromosome segregation by interacting through its coiled-coil domains with several proteins that modulate the G2/M phase. Phosphorylation by Nek2 is essential for faithful chromosome segregation. Required for the recruitment of Mps1 kinase and Mad1/Mad2 complexes to kinetochores. |
Reactivity | Human, Mouse |
Tested applications | WB IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 73 kDa |
Recommended Dilutions |
WB 1:500-1:3000
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide derived from human HEC1 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | HEC, HEC1, Highly expressed in cancer protein, highly expressed in cancer, rich in leucine heptad repeats, HsHec1, hsNDC80, kinetochore associated 2, Kinetochore protein Hec1, Kinetochore protein NDC80 homolog, Kinetochore-associated protein 2, KNTC2, NDC |
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