| No | Size | Price | Availability | |
| ARP8797-61 | 50ul | 1500.00 | In Stock |  |
| ARP8797-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 8797 |
| Isotype: | IgG | Swiss Prot: | O00220 |
| purity: | Affinity chromatography |
| Background: |
| TRAIL-R1 Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B. |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 50 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
|
| Immunogen | A synthetic peptide derived from human TR10A |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | APO2, CD261, cytotoxic TRAIL receptor, Death receptor 4, DR4, MGC9365, TNF-related apoptosis inducing ligand receptor 1, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TR10A, TRAIL receptor 1, TRAIL-R1, TRAILR-1, TRAILR1, Tumor necrosis fact |
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