Source: | Rabbit | Gene Id: | 7518 |
Isotype: | IgG | Swiss Prot: | Q13426 |
purity: | Affinity chromatography |
Background: |
XRCC4 Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. Belongs to the XRCC4 family. |
Reactivity | Human |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 40 kDa |
Recommended Dilutions |
WB 1:500-1:3000
|
Immunogen | A synthetic peptide derived from human XRCC4 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | DNA repair protein XRCC4, X-ray repair complementing defective repair in Chinese hamster cells 4, X-ray repair cross complementing protein 4, X-ray repair cross-complementing protein 4, X-ray repair, complementing defective, repair in Chinese hamster, XR |
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