Source: | Rabbit | Gene Id: | 7507 |
Isotype: | IgG | Swiss Prot: | P23025 |
purity: | Affinity chromatography |
Background: |
XPA Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation. |
Reactivity | Human, Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 40 kDa |
Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human XPA |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | DNA repair protein complementing XP-A cells, excision repair-controlling, Xeroderma pigmentosum group A-complementing protein, xeroderma pigmentosum, complementation group A, XP1, XPA, XPAC |
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