
| Source: | Rabbit | Gene Id: | 51366 |
| Isotype: | IgG | Swiss Prot: | O95071 |
| purity: | Affinity chromatography |
| Background: |
| UBR5 E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 309 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human EDD |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | DD5, E3 identified by differential display, E3 ubiquitin protein ligase, HECT domain containing, 1, E3 ubiquitin-protein ligase UBR5, E3 ubiquitin-protein ligase, HECT domain-containing 1, EDD, EDD1, FLJ11310, hHYD, HYD, Hyperplastic discs protein homolog |
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