Source: | Rabbit | Gene Id: | 10055 |
Isotype: | IgG | Swiss Prot: | Q9UBE0 |
purity: | Affinity chromatography |
Background: |
UBLE1A The dimeric enzyme acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2. Belongs to the ubiquitin-activating E1 family. Heterodimer of SAE1 and SAE2. The complex binds SUMO proteins via SAE2. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 38 kDa |
Recommended Dilutions |
WB 1:500-1:3000
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide derived from human AOS1 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | activator of SUMO1, AOS1, FLJ3091, HSPC140, SAE1, sentrin/SUMO-activating protein AOS1, SUA1, SUMO-1 activating enzyme E1 N subunit, SUMO-1 activating enzyme subunit 1, SUMO-activating enzyme subunit 1, SUMO1 activating enzyme subunit 1, Ubiquitin-like 1 |
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