SHPS1 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP140885-61 50ul 1500.00 In Stock
ARP140885-61 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 140885
Isotype: IgG Swiss Prot: P78324
purity: Affinity chromatography
Background:
SHPS1 Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation.
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 55 kDa
Recommended Dilutions
WB 1:500-1:3000
IHC 1:50-1:200
Immunogen A synthetic peptide derived from human SHPS1
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym BIT, Brain Ig-like molecule with tyrosine-based activation motifs, brain-immunoglobulin-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, CD172A, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MFR, MYD-1, M
This product is for research use only, not for diagnostic or therapeutic use!

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