
| Source: | Rabbit | Gene Id: | 6016 |
| Isotype: | IgG | Swiss Prot: | Q92963 |
| purity: | Affinity chromatography |
| Background: |
| RIT1 Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF- dependent neuronal differentiation. Belongs to the small GTPase superfamily. Ras family. Interacts with MLLT4, the C-terminal domain of RALGDS and RLF, but not with RIN1 and PIK3CA. RLF binds exclusively to the active GTP-bound form. |
| Reactivity | Human, Mouse |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 25 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
|
| Immunogen | A synthetic peptide derived from human RIT1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | GTP-binding protein Rit1, GTP-binding protein Roc1, MGC125864, MGC125865, Ras-like protein expressed in many tissues, Ras-like without CAAX 1, Ras-like without CAAX protein 1, RIBB, Ric-like, expressed in many tissues, RIT, RIT1, ROC1 |
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