| No | Size | Price | Availability | |
| ARP5663-61 | 50ul | 1500.00 | In Stock |  |
| ARP5663-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5663 |
| Isotype: | IgG | Swiss Prot: | P49768 |
| purity: | Affinity chromatography |
| Background: |
| PSEN1 probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. Regulates epithelial- cadherin function. |
| Reactivity | Human |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 60 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human Presenilin 1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | AD3, FAD, presenilin 1, Presenilin-1, Presenilin-1 CTF subunit, Presenilin-1 CTF12, Presenilin-1 NTF subunit, Protein S182, PS-1, PS1, PS1-CTF12, PSEN1, PSN1, PSNL1, S182 |
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