| No | Size | Price | Availability | |
| ARP8626-61 | 50ul | 1500.00 | In Stock |  |
| ARP8626-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 8626 |
| Isotype: | IgG | Swiss Prot: | Q9H3D4 |
| purity: | Affinity chromatography |
| Background: |
| p63 Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of TP53/p53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 77 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human p63 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | identical protein binding, protein binding, DNA binding, p53 binding, sequence-specific DNA binding, metal ion binding, double-stranded DNA binding, damaged DNA binding, chromatin binding, transcription factor activity |
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