Source: | Rabbit | Gene Id: | 5451 |
Isotype: | IgG | Swiss Prot: | P14859 |
purity: | Affinity chromatography |
Background: |
POU2F1 a ubiquitous transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. Phosphorylation apparently inhibits its interaction with DNA |
Reactivity | Human, Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 76 kDa |
Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human 41183 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | NF-A1, Oct-1, OCT1, Octamer-binding protein 1, Octamer-binding transcription factor 1, Octamer-binding transcription factor-1, OTF-1, OTF1, PO2F1, POU class 2 homeobox 1, POU domain, class 2, transcription factor 1, POU2F1 |
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