| No | Size | Price | Availability | |
| ARP4318-61 | 50ul | 1500.00 | In Stock |  |
| ARP4318-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4318 |
| Isotype: | IgG | Swiss Prot: | P14780 |
| purity: | Affinity chromatography |
| Background: |
| MMP9 May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. Belongs to the peptidase M10A family. Activated by 4-aminophenylmercuric acetate and phorbol ester. Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with a 25 kDa protein. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1. |
| Reactivity | Human |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 78 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human MMP9 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | 67 kDa matrix metalloproteinase-9, 82 kDa matrix metalloproteinase-9, 92 kDa gelatinase, 92 kDa type IV collagenase, CLG4B, Gelatinase B, GELB, macrophage gelatinase, MANDP2, matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collage |
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