Source: | Rabbit | Gene Id: | 3868 |
Isotype: | IgG | Swiss Prot: | P08779 |
purity: | Affinity chromatography |
Background: |
K16 a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Generally associates with K6. K16 and K17 are coexpressed only in pathological situations such as metaplasias and carcinomas of the uterine cervix and in psoriasis vulgaris. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 52 kDa |
Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human Keratin 16 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CK-16, CK16, cytokeratin 16, Cytokeratin-16, FNEPPK, focal non-epidermolytic palmoplantar keratoderma, K16, K1C16, K1CP, keratin 16, Keratin, type I cytoskeletal 16, Keratin-16, KRT16, KRT16A, NEPPK |
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