Source: | Rabbit | Gene Id: | 3084 |
Isotype: | IgG | Swiss Prot: | Q02297-10 |
purity: | Affinity chromatography |
Background: |
NRG1 Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 44 kDa |
Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human NRG1 isoform-10 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, GGF, GGF2, Glial growth factor, Heregulin, heregulin, alpha (45kD, ERBB2 p185-activator), HGL, HRG, HRG1, HRGA, NDF, Neu differentiation factor, neuregulin 1 |
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