| No | Size | Price | Availability | |
| ARPF080-61 | 50ul | 1500.00 | In Stock |  |
| ARPF080-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2999/3002 |
| Isotype: | IgG | Swiss Prot: | P20718/P10144 |
| purity: | Affinity chromatography |
| Background: |
| GZMB This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. Belongs to the peptidase S1 family. Granzyme subfamily. Induced by staphylococcal enterotoxin A (SEA) in peripheral blood leukocytes. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 28 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human Granzyme B |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | C11, Cathepsin G-like 1, CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA-1, CTLA1, CTSGL1, cytotoxic serine protease B, Cytotoxic T-lymphocyte proteinase 2, fragmentin 2, Fragmentin-2, GRAB, Granzyme B, granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serin |
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