Source: | Rabbit | Gene Id: | 356 |
Isotype: | IgG | Swiss Prot: | P48023 |
purity: | Affinity chromatography |
Background: |
FasL Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. |
Reactivity | Human, Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 33 kDa |
Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human FASL |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Apoptosis antigen ligand, APT1LG1, APTL, CD95 ligand, CD95-L, CD95L, Fas antigen ligand, Fas ligand, FASL, FASLG, TNFSF6, Tumor necrosis factor ligand superfamily member 6Gene Symbols: FASLG |
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