CREB-BP Rabbit Polyclonal Antibody
No Size Price Availability  
ARP1387-61 50ul 1500.00 In Stock
ARP1387-61 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 1387
Isotype: IgG Swiss Prot: Q92793
purity: Affinity chromatography
Background:
CBP a protein acetyltransferase that can transcriptionally activate histones. Acetylates the NCOA3 coactivator. Binds specifically to phosphorylated CREB1 and enhances its transcriptional activity toward cAMP-responsive genes. Methylation of the KIX domain by CARM1 blocks association with CREB, blocking CREB signaling, and activating the apoptotic response. Found in a complex containing NCOA2, NCOA3, IKKA, IKKB, and IKBKG. Probably part of a complex with HIF1A and EP300.
Reactivity Human, Mouse
Tested applications WB IHC IF ICC
Clonality Polyclonal Antibody
Calculated MW 265 kDa
Recommended Dilutions
WB 1:500-1:3000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
Immunogen A synthetic peptide derived from human CREB-BP
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym CBP, CREB binding protein, CREB-binding protein, CREBBP, KAT3A, RSTS
This product is for research use only, not for diagnostic or therapeutic use!

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