Source: | Rabbit | Gene Id: | 1278 |
Isotype: | IgG | Swiss Prot: | P08123 |
purity: | Affinity purification |
Background: |
This gene encodes one of the chains for type I collagen, the fibrillar collagen found in most connective tissues. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for alpha-1 type I collagen since alpha-2 is less abundant. Multiple messages for this gene result from multiple polyadenylation signals, a feature shared by most of the other collagen genes. |
Reactivity | Human, Mouse, Rat |
Tested applications | IHC IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 129 kDa |
Recommended Dilutions |
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide derived from human Collagen I |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Collagen alpha-2(I) chain [Precursor], Alpha-2 type I collagen, CO1A2 |
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