| No | Size | Price | Availability | |
| ARP857-61 | 50ul | 1500.00 | In Stock |  |
| ARP857-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 857 |
| Isotype: | IgG | Swiss Prot: | Q03135 |
| purity: | Affinity chromatography |
| Background: |
| The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 25 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human CAV1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CAV1, BSCL3, CAV, CGL3, MSTP085, VIP21 |
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