Source: | Rabbit | Gene Id: | 578 |
Isotype: | IgG | Swiss Prot: | Q16611 |
purity: | Affinity chromatography |
Background: |
Bak1 In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis. Belongs to the Bcl-2 family. Interacts with BCL2A1. Homodimer. Formation of the homodimer is zinc-dependent. Forms heterodimers with BCL2, E1B 19k protein, and BCL2L1 isoform Bcl-X(L). Interacts with myxoma virus protein M11L |
Reactivity | Human, Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 25 kDa |
Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human Bak |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Apoptosis regulator BAK, BAK, BAK-LIKE, BAK1, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 7, BCL2-antagonist/killer 1, Bcl2-L-7, BCL2-like 7 protein, BCL2L7, CDN1, MGC117255, MGC3887, pro-apoptotic protein BAK |
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