Source: | Rabbit | Gene Id: | 5884 |
Isotype: | IgG | Swiss Prot: | O75943 |
purity: | Affinity chromatography |
Background: |
Rad17 a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. Shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. Binds to chromatin prior to DNA damage and is phosphorylated by ATR after the damage. Phosphorylated and activated after DNA damage, inducing cell cycle G2 arrest. Eight alternatively spliced variants have been reported. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 77 kDa |
Recommended Dilutions |
WB 1:500-1:3000
|
Immunogen | A synthetic peptide derived from human RAD17 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CCYC, cell cycle checkpoint protein (RAD17), Cell cycle checkpoint protein RAD17, FLJ41520, hRad17, R24L, RAD1 homolog, RAD17, RAD17 homolog (S. pombe), Rad17-like protein, RAD17SP, RAD24, RF-C activator 1 homolog, RF-C/activator 1 homolog |
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