Source: | Rabbit | Gene Id: | 7272 |
Isotype: | IgG | Swiss Prot: | P33981 |
purity: | Affinity chromatography |
Background: |
TTK a dual-specificity protein kinase orthologous to the yeast monopolar spindle (Mps1) kinase that is required for spindle pole duplication and the spindle checkpoint but not for centrosome duplication. Localized to centrosomes, kinetochores and nuclear pores. Its enzymatic activity is required for the recruitment of Mad1, Mad2, Bub1 and Bub3 to the kinetochore. |
Reactivity | Human, Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 100 kDa |
Recommended Dilutions |
WB 1:500~1:3000
IHC 1:50~1:200
|
Immunogen | A synthetic peptide derived from human TTK |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | cancer/testis antigen 96, CT96, Dual specificity protein kinase TTK, ESK, FLJ38280, monopolar spindle 1-like 1, MPS1, MPS1L1, phosphotyrosine picked threonine kinase, Phosphotyrosine picked threonine-protein kinase, PYT, TTK, TTK protein kinase |
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