Source: | Rabbit | Gene Id: | 4846 |
Isotype: | IgG | Swiss Prot: | P29474 |
purity: | Affinity chromatography |
Background: |
eNOS endothelial constitutive nitric oxide synthase. Synthesizes nitric oxide (NO) from arginine and oxygen, which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Induced in humans by caloric restriction. Stimulated by calcium/calmodulin. Inhibited by NOSIP and NOSTRIN. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 140 kDa |
Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human eNOS |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | cNOS, Constitutive NOS, EC-NOS, ECNOS, Endothelial NOS, eNOS, nitric oxide synthase 3 (endothelial cell), Nitric oxide synthase, endothelial, NOS type III, NOS3, NOSIII |
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