Source: | Rabbit | Gene Id: | 1969 |
Isotype: | IgG | Swiss Prot: | P29317/P29320/P54764 |
purity: | Affinity purification |
Background: |
EphA2 a receptor tyrosine kinase. Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 AND -A5. The Eph receptor tyrosine kinase family, the largest in the tyrosine kinase group, has fourteen members. They bind membrane-anchored ligands, ephrins, at sites of cell-cell contact, regulating the repulsion and adhesion of cells that underlie the establishment, maintenance, and remodeling of patterns of cellular organization. Eph signals are particularly important in regulating cell adhesion and cell migration during development, axon guidance, homeostasis and disease. |
Reactivity | Human, Rat |
Tested applications | WB IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 130 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide derived from human EPHA2/3/4 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | ARCC2, ECK, EPH receptor A2, EPHA2, ephrin receptor EphA2, Ephrin type-A receptor 2, Epithelial cell kinase, epithelial cell receptor protein tyrosine kinase, protein tyrosine kinase, soluble EPHA2 variant 1, Tyrosine-protein kinase receptor ECK |
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