| No | Size | Price | Availability | |
| ARP5829P-61 | 50ul | 1500.00 | In Stock |  |
| ARP5829P-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5829 |
| Isotype: | IgG | Swiss Prot: | P49023 |
| purity: | Affinity purification |
| Background: |
| PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions. The SH2 domain of Crk binds to tyrosine phosphorylated paxillin. Three alternatively-spliced isoforms have been described. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 64 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A synthetic peptide derived from human Paxillin around the phosphorylation site of Sersine 178 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Paired box protein Pax-1, PAX-1, PAXI, paxillin, paxillin alpha |
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