Source: | Rabbit | Gene Id: | 5914 |
Isotype: | IgG | Swiss Prot: | P10276 |
purity: | Affinity purification |
Background: |
RARA is a receptor for retinoic acid, a potent mammalian morphogen and teratogen that has profound effects on vertebrate development. RARA is a member of the nuclear receptor superfamily. Controls cell function by directly regulating gene expression. Its phosphorylation is crucial for transcriptional activity. Aberrations involving RARA may be a cause of acute promyelocytic leukemia. Two splice-variant isoforms have been described. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 45 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human Retinoic Acid Receptor alpha around the phosphorylation site of Sersine 77 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | NR1B1, RAR-alpha, Retinoic acid receptor alpha, retinoic acid receptor, alpha, RRA |
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