| No | Size | Price | Availability | |
| ARP3184P-61 | 50ul | 1500.00 | In Stock |  |
| ARP3184P-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3184 |
| Isotype: | IgG | Swiss Prot: | Q14103 |
| purity: | Affinity purification |
| Background: |
| This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 38 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human hnRPD around the phosphorylation site of Sersine 83 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | ARE element RNA-binding protein AUF1, AU-rich element RNA-binding protein 1, AUF1, HNRPD, Heterogeneous nuclear ribonucleoprotein D, Heterogeneous nuclear ribonucleoprotein D0, ROD |
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