| No | Size | Price | Availability | |
| ARP6416P-02 | 50ul | 1500.00 | In Stock |  |
| ARP6416P-02 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6416 |
| Isotype: | IgG | Swiss Prot: | P45985 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 44 kDa |
| Recommended Dilutions |
IHC 1:50-1:100
IF 1:100-1:200
|
| Immunogen | A phospho specific peptide corresponding to residues surrounding T261 of human MAP2K4 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | JNKK, MEK4, MKK4, SEK1, SKK1, JNKK1, SERK1, MAPKK4, PRKMK4, SAPKK1, SAPKK-1 |
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