Source: | Rabbit | Gene Id: | 995 |
Isotype: | IgG | Swiss Prot: | P30307 |
purity: | Affinity purification |
Background: |
This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. |
Reactivity | Human |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | 80 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:100
IF 1:100-1:200
|
Immunogen | A phospho specific peptide corresponding to residues surrounding S216 of human CDC25C |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CDC25, PPP1R60 |
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