| No | Size | Price | Availability | |
| ARP31P-01 | 50ul | 1500.00 | In Stock |  |
| ARP31P-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 31 |
| Isotype: | IgG | Swiss Prot: | Q13085 |
| purity: | Affinity purification |
| Background: |
| Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 265 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A phospho specific peptide corresponding to residues surrounding S79 of human ACACA |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | ACC, ACAC, ACC1, ACCA, ACACAD |
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