| No | Size | Price | Availability | |
| ARP6773P-01 | 50ul | 1500.00 | In Stock |  |
| ARP6773P-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6773 |
| Isotype: | IgG | Swiss Prot: | P52630 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 113 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A phospho specific peptide corresponding to residues surrounding Y690 of human STAT2 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | P113, ISGF-3, STAT113 |
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