| No | Size | Price | Availability | |
| ARP613P-01 | 50ul | 1500.00 | In Stock |  |
| ARP613P-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 613 |
| Isotype: | IgG | Swiss Prot: | P11274 |
| purity: | Affinity purification |
| Background: |
| A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 210 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:100
|
| Immunogen | A phospho specific peptide corresponding to residues surrounding Y177 of human BCR |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | ALL, BCR-ABL1, BCR1, CML, D22S11, D22S662, FLJ16453, PHL |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
