| Source: | Rabbit | Gene Id: | 1386 |
| Isotype: | IgG | Swiss Prot: | P15336 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 65-75 kDa |
| Recommended Dilutions |
WB 1:500 - 1:1000
IHC 1:50 - 1:100
IF 1:50 - 1:100
|
| Immunogen | A phospho specific peptide corresponding to residues surrounding T53 of_+E_human ATF2 |
| Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | CREB2, CRE-BP1 |
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