| No | Size | Price | Availability | |
| ARP673P-11 | 50ul | 1500.00 | In Stock |  |
| ARP673P-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 673 |
| Isotype: | / | Swiss Prot: | P15056 |
| purity: | Protein A purification |
| Background: |
| This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | ELISA Dot |
| Clonality | Polyclonal Antibody |
| Calculated MW | 86 kDa |
| Recommended Dilutions | |
| Immunogen | A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S445 of human BRAF |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | B-RAF1, BRAF1, FLJ95109, MGC126806, MGC138284, RAFB1 |
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