| No | Size | Price | Availability | |
| ARP4609P-01 | 50ul | 1500.00 | In Stock |  |
| ARP4609P-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4609 |
| Isotype: | IgG | Swiss Prot: | P05067 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 87kDa |
| Recommended Dilutions |
WB 1:500 - 1:1000
IHC 1:50 - 1:100
|
| Immunogen | A phospho specific peptide corresponding to residues surrounding T743 of_+E_human APP |
| Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, PN-II, CTFgamma |
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